Aspadol 100 mg, like other opioids, can cause respiratory depression, especially in high doses or when combined with other central nervous system depressants. It is important to use the lowest effective dose for the shortest possible duration to minimize this risk.

Tapentadol, the active ingredient in Aspadol 100 mg, has a potential for abuse and addiction, especially in individuals with a history of substance abuse or addiction.
Combining aspadol 100 mg with alcohol or other central nervous system depressants may increase the risk of respiratory depression, sedation, and other adverse effects. While using Aspadol 100 mg it is important to avoid alcohol and consult your healthcare provider before taking other medications.

Abrupt discontinuation of Aspadol 100 mg after prolonged use may cause withdrawal symptoms including anxiety, agitation, insomnia, sweating, and muscle pain. It is important to reduce the dose gradually under the supervision of a healthcare provider to reduce the risk of withdrawal.

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